Highly competent, non-exhausted CD8+ T cells continue to tightly control pathogen load throughout chronic Trypanosoma cruzi infection

Trypanosoma cruzi infection is characterized by chronic parasitism of non-lymphoid tissues and is rarely eliminated despite potent adaptive immune responses. This failure to cure has frequently been attributed to a loss or impairment of anti-T. cruzi T cell responses over time, analogous to the T ce...

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Detalles Bibliográficos
Autores principales: Pack, Angela D., Collins, Matthew H., Rosenberg, Charles S., Tarleton, Rick L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6258465/
https://www.ncbi.nlm.nih.gov/pubmed/30419010
http://dx.doi.org/10.1371/journal.ppat.1007410

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6258465/
https://www.ncbi.nlm.nih.gov/pubmed/30419010
http://dx.doi.org/10.1371/journal.ppat.1007410

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