Cargando…
Highly competent, non-exhausted CD8+ T cells continue to tightly control pathogen load throughout chronic Trypanosoma cruzi infection
Trypanosoma cruzi infection is characterized by chronic parasitism of non-lymphoid tissues and is rarely eliminated despite potent adaptive immune responses. This failure to cure has frequently been attributed to a loss or impairment of anti-T. cruzi T cell responses over time, analogous to the T ce...
Autores principales: | Pack, Angela D., Collins, Matthew H., Rosenberg, Charles S., Tarleton, Rick L. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6258465/ https://www.ncbi.nlm.nih.gov/pubmed/30419010 http://dx.doi.org/10.1371/journal.ppat.1007410 |
Ejemplares similares
-
Recombination-driven generation of the largest pathogen repository of antigen variants in the protozoan Trypanosoma cruzi
por: Weatherly, D. Brent, et al.
Publicado: (2016) -
Chromosome level assembly of the hybrid Trypanosoma cruzi genome
por: Weatherly, D Brent, et al.
Publicado: (2009) -
CD8(+) T-Cell Responses to Trypanosoma cruzi Are Highly Focused on Strain-Variant trans-Sialidase Epitopes
por: Martin, Diana L, et al.
Publicado: (2006) -
Evaluation of high efficiency gene knockout strategies for Trypanosoma cruzi
por: Xu, Dan, et al.
Publicado: (2009) -
Identification of Contractile Vacuole Proteins in Trypanosoma
cruzi
por: Ulrich, Paul N., et al.
Publicado: (2011)