An evaluation of TAZ and YAP crosstalk with TGFβ signalling in canine osteosarcoma suggests involvement of hippo signalling in disease progression

BACKGROUND: Osteosarcoma (OSA) is the most common bone cancer in canines. Both transforming growth factor beta (TGFβ) and Hippo pathway mediators have important roles in bone development, stemness, and cancer progression. The role of Hippo signalling effectors TAZ and YAP has never been addressed in...

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Detalles Bibliográficos
Autores principales: Luu, Anita K., Schott, Courtney R., Jones, Robert, Poon, Andrew C., Golding, Brandon, Hamed, Roa’a, Deheshi, Benjamin, Mutsaers, Anthony, Wood, Geoffrey A., Viloria-Petit, Alicia M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6258471/
https://www.ncbi.nlm.nih.gov/pubmed/30477496
http://dx.doi.org/10.1186/s12917-018-1651-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6258471/
https://www.ncbi.nlm.nih.gov/pubmed/30477496
http://dx.doi.org/10.1186/s12917-018-1651-5

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