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Modeling craniofacial development reveals spatiotemporal constraints on robust patterning of the mandibular arch

How does pattern formation occur accurately when confronted with tissue growth and stochastic fluctuations (noise) in gene expression? Dorso-ventral (D-V) patterning of the mandibular arch specifies upper versus lower jaw skeletal elements through a combination of Bone morphogenetic protein (Bmp), E...

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Detalles Bibliográficos
Autores principales: Meinecke, Lina, Sharma, Praveer P., Du, Huijing, Zhang, Lei, Nie, Qing, Schilling, Thomas F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6258504/
https://www.ncbi.nlm.nih.gov/pubmed/30481168
http://dx.doi.org/10.1371/journal.pcbi.1006569