Remodeling the endoplasmic reticulum proteostasis network restores proteostasis of pathogenic GABA(A) receptors

Biogenesis of membrane proteins is controlled by the protein homeostasis (proteostasis) network. We have been focusing on protein quality control of γ-aminobutyric acid type A (GABA(A)) receptors, the major inhibitory neurotransmitter-gated ion channels in mammalian central nervous system. Proteosta...

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Detalles Bibliográficos
Autores principales: Fu, Yan-Lin, Han, Dong-Yun, Wang, Ya-Juan, Di, Xiao-Jing, Yu, Hai-Bo, Mu, Ting-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6258528/
https://www.ncbi.nlm.nih.gov/pubmed/30481215
http://dx.doi.org/10.1371/journal.pone.0207948

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6258528/
https://www.ncbi.nlm.nih.gov/pubmed/30481215
http://dx.doi.org/10.1371/journal.pone.0207948

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