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Remodeling the endoplasmic reticulum proteostasis network restores proteostasis of pathogenic GABA(A) receptors
Biogenesis of membrane proteins is controlled by the protein homeostasis (proteostasis) network. We have been focusing on protein quality control of γ-aminobutyric acid type A (GABA(A)) receptors, the major inhibitory neurotransmitter-gated ion channels in mammalian central nervous system. Proteosta...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6258528/ https://www.ncbi.nlm.nih.gov/pubmed/30481215 http://dx.doi.org/10.1371/journal.pone.0207948 |