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Single cell RNA-sequencing identifies a metabolic aspect of apoptosis in Rbf mutant

The function of Retinoblastoma tumor suppressor (pRB) is greatly influenced by the cellular context, therefore the consequences of pRB inactivation are cell-type-specific. Here we employ single cell RNA-sequencing (scRNA-seq) to profile the impact of an Rbf mutation during Drosophila eye development...

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Detalles Bibliográficos
Autores principales: Ariss, Majd M., Islam, Abul B. M. M. K., Critcher, Meg, Zappia, Maria Paula, Frolov, Maxim V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6258665/
https://www.ncbi.nlm.nih.gov/pubmed/30479347
http://dx.doi.org/10.1038/s41467-018-07540-z