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Hysteresis control of epithelial-mesenchymal transition dynamics conveys a distinct program with enhanced metastatic ability

Epithelial-mesenchymal transition (EMT) have been extensively characterized in development and cancer, and its dynamics have been modeled as a non-linear process. However, less is known about how such dynamics may affect its biological impact. Here, we use mathematical modeling and experimental anal...

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Detalles Bibliográficos
Autores principales: Celià-Terrassa, Toni, Bastian, Caleb, Liu, Daniel D., Ell, Brian, Aiello, Nicole M., Wei, Yong, Zamalloa, Jose, Blanco, Andres M., Hang, Xiang, Kunisky, Dmitriy, Li, Wenyang, Williams, Elizabeth D., Rabitz, Herschel, Kang, Yibin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6258667/
https://www.ncbi.nlm.nih.gov/pubmed/30479345
http://dx.doi.org/10.1038/s41467-018-07538-7