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Genome-wide DNA methylation changes in CD19(+) B cells from relapsing-remitting multiple sclerosis patients

Multiple Sclerosis (MS) is an inflammatory and neurodegenerative disease of the central nervous system. The inflammatory process in MS is driven by both T and B cells and current therapies are targeted to each of these cell types. Epigenetic mechanisms may provide a valuable link between genes and e...

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Detalles Bibliográficos
Autores principales: Maltby, Vicki E., Lea, Rodney A., Graves, Moira C., Sanders, Katherine A., Benton, Miles C., Tajouri, Lotti, Scott, Rodney J., Lechner-Scott, Jeannette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6258668/
https://www.ncbi.nlm.nih.gov/pubmed/30479356
http://dx.doi.org/10.1038/s41598-018-35603-0