Type 1 Diabetes Mellitus-Associated Genetic Variants Contribute to Overlapping Immune Regulatory Networks

Type 1 diabetes (T1D) is a chronic metabolic disorder characterized by the autoimmune destruction of insulin-producing pancreatic islet beta cells in genetically predisposed individuals. Genome-wide association studies (GWAS) have identified over 60 risk regions across the human genome, marked by si...

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Detalles Bibliográficos
Autores principales: Nyaga, Denis M., Vickers, Mark H., Jefferies, Craig, Perry, Jo K., O’Sullivan, Justin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6258722/
https://www.ncbi.nlm.nih.gov/pubmed/30524468
http://dx.doi.org/10.3389/fgene.2018.00535

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6258722/
https://www.ncbi.nlm.nih.gov/pubmed/30524468
http://dx.doi.org/10.3389/fgene.2018.00535

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