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Dysfunction of IKZF1/MYC/MDIG axis contributes to liver cancer progression through regulating H3K9me3/p21 activity

MDIG is known to be overexpressed in many types of human cancers and has demonstrated predictive power in the prognosis of cancer, although the functions and mechanisms of MDIG in liver cancer, especially in hepatocellular carcinoma (HCC), are still unknown. In this study, we report that MDIG and MY...

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Detalles Bibliográficos
Autores principales: Huo, Qi, Ge, Chao, Tian, Hua, Sun, Ji, Cui, Meiling, Li, Hong, Zhao, Fangyu, Chen, Taoyang, Xie, Haiyang, Cui, Ying, Yao, Ming, Li, Jinjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6258834/
https://www.ncbi.nlm.nih.gov/pubmed/28471446
http://dx.doi.org/10.1038/cddis.2017.165