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Lentiviral Vector Purification Using Genetically Encoded Biotin Mimic in Packaging Cell

Lentiviral vectors (LVs) have recently witnessed an increasing demand in research and clinical applications. Their current purification processes represent the main bottleneck in their widespread use, as the methods used are cumbersome and yield low recoveries. We aimed to develop a one-step method...

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Detalles Bibliográficos
Autores principales: Mekkaoui, Leila, Parekh, Farhaan, Kotsopoulou, Ekaterini, Darling, David, Dickson, Glenda, Cheung, Gordon W., Chan, Lucas, MacLellan-Gibson, Kirsty, Mattiuzzo, Giada, Farzaneh, Farzin, Takeuchi, Yasuhiro., Pule, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6258877/
https://www.ncbi.nlm.nih.gov/pubmed/30547049
http://dx.doi.org/10.1016/j.omtm.2018.10.008