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Wnt Secretion Is Regulated by the Tetraspan Protein HIC-1 through Its Interaction with Neurabin/NAB-1

The aberrant regulation of Wnt secretion is implicated in various neurological diseases. However, the mechanisms of Wnt release are still largely unknown. Here we describe the role of a C. elegans tetraspan protein, HIC-1, in maintaining normal Wnt release. We show that HIC-1 is expressed in choline...

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Detalles Bibliográficos
Autores principales: Tikiyani, Vina, Li, Lei, Sharma, Pallavi, Liu, Haowen, Hu, Zhitao, Babu, Kavita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6258899/
https://www.ncbi.nlm.nih.gov/pubmed/30428353
http://dx.doi.org/10.1016/j.celrep.2018.10.053