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Phosphatidylinositol 3-Kinase/Akt and MEK/ERK Signaling Pathways Facilitate Sapovirus Trafficking and Late Endosomal Acidification for Viral Uncoating in LLC-PK Cells

Sapovirus, an important cause of acute gastroenteritis in humans and animals, travels from the early to the late endosomes and requires late endosomal acidification for viral uncoating. However, the signaling pathways responsible for these viral entry processes remain unknown. Here we demonstrate th...

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Detalles Bibliográficos
Autores principales: Soliman, Mahmoud, Kim, Deok-Song, Park, Jun-Gyu, Kim, Ji-Yun, Alfajaro, Mia Madel, Baek, Yeong-Bin, Cho, Eun-Hyo, Park, Chul-Ho, Kang, Mun-Il, Park, Sang-Ik, Cho, Kyoung-Oh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6258943/
https://www.ncbi.nlm.nih.gov/pubmed/30282712
http://dx.doi.org/10.1128/JVI.01674-18