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Poly-sarcosine and Poly(Ethylene-Glycol) Interactions with Proteins Investigated Using Molecular Dynamics Simulations

Nanoparticles coated with hydrophilic polymers often show a reduction in unspecific interactions with the biological environment, which improves their biocompatibility. The molecular determinants of this reduction are not very well understood yet, and their knowledge may help improving nanoparticle...

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Detalles Bibliográficos
Autores principales: Settanni, Giovanni, Schäfer, Timo, Muhl, Christian, Barz, Matthias, Schmid, Friederike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6259037/
https://www.ncbi.nlm.nih.gov/pubmed/30524669
http://dx.doi.org/10.1016/j.csbj.2018.10.012