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Modulation of Huntingtin Toxicity by BAG1 is Dependent on an Intact BAG Domain

Huntington´s disease, one of the so-called poly-glutamine diseases, is a dominantly inherited movement disorder characterized by formation of cytosolic and nuclear inclusion bodies and progressive neurodegeneration. Recently, we have shown that Bcl-2-associated athanogene-1 (BAG1), a multifunctional...

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Detalles Bibliográficos
Autores principales: Liman, Jan, Sroka, Kamila, Dohm, Christoph P., Deeg, Sebastian, Bähr, Mathias, Kermer, Pawel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6259099/
http://dx.doi.org/10.3390/molecules15106678