Novel Synthesis and Antitumor Evaluation of Polyfunctionally Substituted Heterocyclic Compounds Derived from 2-Cyano-N-(3-cyano-4,5,6,7-tetrahydrobenzo[b]thiophen-2-yl)-acetamide

The reaction of 2-amino-3-cyano-4,5,6,7-tetrahydrobenzo[b]thiophene with ethyl cyanoacetate gave 2-cyano-N-(3-cyano-4,5,6,7-tetrahydrobenzo[b]thiophen-2-yl)-acetamide. The latter was used to synthesize different heterocyclic derivatives comprising thiophene, thiazole, pyrazole, pyridine, pyrimidine,...

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Detalles Bibliográficos
Autores principales: Shams, Hoda Z., Mohareb, Rafat M., Helal, Maher H., Mahmoud, Amira E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6259152/
https://www.ncbi.nlm.nih.gov/pubmed/21187817
http://dx.doi.org/10.3390/molecules16010052

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6259152/
https://www.ncbi.nlm.nih.gov/pubmed/21187817
http://dx.doi.org/10.3390/molecules16010052

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