A General Synthetic Procedure for 2-chloromethyl-4(3H)-quinazolinone Derivatives and Their Utilization in the Preparation of Novel Anticancer Agents with 4-Anilinoquinazoline Scaffolds

In our ongoing research on novel anticancer agents with 4-anilinoquinazoline scaffolds, a series of novel 2-chloromethyl-4(3H)-quinazolinones were needed as key intermediates. An improved one-step synthesis of 2-chloromethyl-4(3H)-quinazolinones utilizing o-anthranilic acids as starting materials wa...

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Detalles Bibliográficos
Autores principales: Li, Hong-Ze, He, Hai-Yun, Han, Yuan-Yuan, Gu, Xin, He, Lin, Qi, Qing-Rong, Zhao, Ying-Lan, Yang, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6259244/
https://www.ncbi.nlm.nih.gov/pubmed/21178902
http://dx.doi.org/10.3390/molecules15129473

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6259244/
https://www.ncbi.nlm.nih.gov/pubmed/21178902
http://dx.doi.org/10.3390/molecules15129473

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