Synthesis of Non-Cytotoxic Poly(Ester-Amine) Dendrimers as Potential Solubility Enhancers for Drugs: Methotrexate as a Case Study

This study describes the synthesis of two new families of dendrimers based on the esterification of N-alkylated 3-amine-1-propanol with two different cores, adipic acid (1(st) and 2(nd) generations) and ethylenediamine (generation 1.5), both with carboxylic acid end groups, offering a wide variety o...

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Detalles Bibliográficos
Autores principales: Soto-Castro, Delia, Cruz-Morales, Jorge A., Apan, María Teresa Ramírez, Guadarrama, Patricia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6259256/
https://www.ncbi.nlm.nih.gov/pubmed/21063271
http://dx.doi.org/10.3390/molecules15118082

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6259256/
https://www.ncbi.nlm.nih.gov/pubmed/21063271
http://dx.doi.org/10.3390/molecules15118082

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