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Synthesis of Non-Cytotoxic Poly(Ester-Amine) Dendrimers as Potential Solubility Enhancers for Drugs: Methotrexate as a Case Study
This study describes the synthesis of two new families of dendrimers based on the esterification of N-alkylated 3-amine-1-propanol with two different cores, adipic acid (1(st) and 2(nd) generations) and ethylenediamine (generation 1.5), both with carboxylic acid end groups, offering a wide variety o...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6259256/ https://www.ncbi.nlm.nih.gov/pubmed/21063271 http://dx.doi.org/10.3390/molecules15118082 |