Synthesis, Inhibitory Effects on Nitric Oxide and Structure-Activity Relationships of a Glycosphingolipid from the Marine Sponge Aplysinella rhax and Its Analogues

The novel glycosphingolipid, β-D-GalNAcp(1→4)[α-D-Fucp(1→3)]-β-D-GlcNAcp(1→)Cer (A), isolated from the marine sponge Aplysinella rhax has a unique structure, with D-fucose and N-acetyl-D-galactosamine moieties attached to a reducing-end N-acetyl-D-glucosamine through an α1→3 and β1→4 linkage, respec...

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Detalles Bibliográficos
Autores principales: Fujita, Yuzo, Ohshima, Naohiro, Hasegawa, Ai, Schweizer, Frank, Takeda, Tadahiro, Kiuchi, Fumiyuki, Hada, Noriyasu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6259274/
https://www.ncbi.nlm.nih.gov/pubmed/21242943
http://dx.doi.org/10.3390/molecules16010637

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6259274/
https://www.ncbi.nlm.nih.gov/pubmed/21242943
http://dx.doi.org/10.3390/molecules16010637

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