An Efficient New Route to Dihydropyranobenzimidazole Inhibitors of HCV Replication

A class of dihydropyranobenzimidazole inhibitors was recently discovered that acts against the hepatitis C virus (HCV) in a new way, binding to the IRES-IIa subdomain of the highly conserved 5' untranslated region of the viral RNA and thus preventing the ribosome from initiating translation. Ho...

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Detalles Bibliográficos
Autores principales: Parker, Matthew A., Satkiewicz, Emily, Hermann, Thomas, Bergdahl, B. Mikael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6259416/
https://www.ncbi.nlm.nih.gov/pubmed/21193848
http://dx.doi.org/10.3390/molecules16010281

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6259416/
https://www.ncbi.nlm.nih.gov/pubmed/21193848
http://dx.doi.org/10.3390/molecules16010281

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