Novel Synthesis of Hydrazide-Hydrazone Derivatives and Their Utilization in the Synthesis of Coumarin, Pyridine, Thiazole and Thiophene Derivatives with Antitumor Activity

The reaction of cyanoacetyl hydrazine (1) with 3-acetylpyridine (2) gave the hydrazide-hydrazone derivative 3. The latter compound undergoes a series of heterocyclization reactions to give new heterocyclic compounds. The antitumor evaluation of the newly synthesized products against three cancer cel...

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Detalles Bibliográficos
Autores principales: Mohareb, Rafat M., Fleita, Daisy H., Sakka, Ola K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6259419/
https://www.ncbi.nlm.nih.gov/pubmed/21187814
http://dx.doi.org/10.3390/molecules16010016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6259419/
https://www.ncbi.nlm.nih.gov/pubmed/21187814
http://dx.doi.org/10.3390/molecules16010016

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