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Synthesis and Antiviral Activity of 5‑(4‑Chlorophenyl)-1,3,4-Thiadiazole Sulfonamides

Starting from 4-chlorobenzoic acid, 10 new 5-(4-chlorophenyl)-N-substituted-N-1,3,4-thiadiazole-2-sulfonamide derivatives were synthesized in six-steps. Esterification of 4-chlorobenzoic acid with methanol and subsequent hydrazination, salt formation and cyclization afforded 5-(4-chlorophen-yl)-1,3,...

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Detalles Bibliográficos
Autores principales: Chen, Zhuo, Xu, Weiming, Liu, Keming, Yang, Song, Fan, Huitao, Bhadury, Pinaki S., Hu, De-Yu, Zhang, Yuping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6259578/
https://www.ncbi.nlm.nih.gov/pubmed/21150824
http://dx.doi.org/10.3390/molecules15129046