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Comparative Anti-Infectious Bronchitis Virus (IBV) Activity of (-)-Pinene: Effect on Nucleocapsid (N) Protein

In the present study, anti-IBV (infectious bronchitis virus) activities of (-)-pinenes were studied by MTT assay, as well as docking and molecular dynamic (MD) simulations. The CC(50)values of (-)-α-pinene and (-)-β-pinene were above 10 mM. And the maximum noncytotoxic concentrations (TD(0)) of (-)-...

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Detalles Bibliográficos
Autores principales: Yang, Zhiwei, Wu, Nan, Zu, Yuangang, Fu, Yujie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6259611/
https://www.ncbi.nlm.nih.gov/pubmed/21350392
http://dx.doi.org/10.3390/molecules16021044