Tamm-Horsfall Glycoprotein Enhances PMN Phagocytosis by Binding to Cell Surface-Expressed Lactoferrin and Cathepsin G That Activates MAP Kinase Pathway

The molecular basis of polymorphonuclear neutrophil (PMN) phagocytosis-enhancing activity (PEA) by human purified urinary Tamm-Horsfall glyco- protein (THP) has not been elucidated. In this study, we found human THP bound to lactoferrin (LF) and cathepsin G (CG) expressed on the surface of PMN, iden...

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Detalles Bibliográficos
Autores principales: Siao, Syue-Cian, Li, Ko-Jen, Hsieh, Song-Chou, Wu, Cheng-Han, Lu, Ming-Chi, Tsai, Chang-Youh, Yu, Chia-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6259617/
https://www.ncbi.nlm.nih.gov/pubmed/21372759
http://dx.doi.org/10.3390/molecules16032119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6259617/
https://www.ncbi.nlm.nih.gov/pubmed/21372759
http://dx.doi.org/10.3390/molecules16032119

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