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Challenges in Optimizing a Prostate Carcinoma Binding Peptide, Identified through the Phage Display Technology

The transfer of peptides identified through the phage display technology to clinical applications is difficult. Major drawbacks are the metabolic degradation and label instability. The aim of our work is the optimization of DUP-1, a peptide which was identified by phage display to specifically targe...

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Detalles Bibliográficos
Autores principales: Askoxylakis, Vasileios, Zitzmann-Kolbe, Sabine, Zoller, Frederic, Altmann, Annette, Markert, Annette, Rana, Shoaib, Marr, Annabell, Mier, Walter, Debus, Jürgen, Haberkorn, Uwe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6259618/
https://www.ncbi.nlm.nih.gov/pubmed/21321528
http://dx.doi.org/10.3390/molecules16021559