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Enaminones as Building Blocks for the Synthesis of Substituted Pyrazoles with Antitumor and Antimicrobial Activities
Novel N-arylpyrazole-containing enaminones 2a,b were synthesized as key intermediates. Reactions of 2a,b with active methylene compounds in acetic acid in the presence of ammonium acetate afforded substituted pyridine derivatives 5a-d. Enaminones 2a,b also reacted with aliphatic amines such as hydra...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6259914/ https://www.ncbi.nlm.nih.gov/pubmed/21343888 http://dx.doi.org/10.3390/molecules16021834 |