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P2X1 Receptors Amplify FcγRIIa-Induced Ca (2+) Increases and Functional Responses in Human Platelets

Platelets express key receptors of the innate immune system such as FcγRIIa and Toll-like receptors (TLR). P2X1 cation channels amplify the platelet responses to several major platelet stimuli, particularly glycoprotein (GP)VI and TLR2/1, whereas their contribution to Src tyrosine kinase-dependent F...

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Detalles Bibliográficos
Autores principales: Ilkan, Zeki, Watson, Stephanie, Watson, Steve P., Mahaut-Smith, Martyn P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Schattauer GmbH 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260114/
https://www.ncbi.nlm.nih.gov/pubmed/29443373
http://dx.doi.org/10.1160/TH17-07-0530