Single-dose ciraparantag safely and completely reverses anticoagulant effects of edoxaban

Of the new direct oral anticoagulants, direct factor Xa inhibitors are limited by the absence of a proven reversal agent. We assessed the safety, tolerability and impact on anticoagulation reversal of ciraparantag (PER977) alone and following a 60 mg dose of the FXa inhibitor edoxaban. Escalating, s...

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Detalles Bibliográficos
Autores principales: Ansell, Jack E., Bakhru, Sasha H., Laulicht, Bryan E., Steiner, Solomon S., Grosso, Michael A., Brown, Karen, Dishy, Victor, Lanz, Hans J., Mercuri, Michele F., Noveck, Robert J., Costin, James C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Schattauer GmbH 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260118/
https://www.ncbi.nlm.nih.gov/pubmed/27853809
http://dx.doi.org/10.1160/TH16-03-0224

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260118/
https://www.ncbi.nlm.nih.gov/pubmed/27853809
http://dx.doi.org/10.1160/TH16-03-0224

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