Antigen recognition by single-domain antibodies: structural latitudes and constraints

Single-domain antibodies (sdAbs), the autonomous variable domains of heavy chain-only antibodies produced naturally by camelid ungulates and cartilaginous fishes, have evolved to bind antigen using only three complementarity-determining region (CDR) loops rather than the six present in conventional...

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Detalles Bibliográficos
Autores principales: Henry, Kevin A., MacKenzie, C. Roger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260137/
https://www.ncbi.nlm.nih.gov/pubmed/29916758
http://dx.doi.org/10.1080/19420862.2018.1489633

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260137/
https://www.ncbi.nlm.nih.gov/pubmed/29916758
http://dx.doi.org/10.1080/19420862.2018.1489633

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