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Antigen recognition by single-domain antibodies: structural latitudes and constraints
Single-domain antibodies (sdAbs), the autonomous variable domains of heavy chain-only antibodies produced naturally by camelid ungulates and cartilaginous fishes, have evolved to bind antigen using only three complementarity-determining region (CDR) loops rather than the six present in conventional...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Taylor & Francis
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260137/ https://www.ncbi.nlm.nih.gov/pubmed/29916758 http://dx.doi.org/10.1080/19420862.2018.1489633 |