Glucose deprivation promotes apoptotic response to S1 by enhancing autophagy in human cervical cancer cells

BACKGROUND: S1 is a novel BH3 mimetic that can induce death in some types of cancer cells, such as melanoma B16, ovarian cancer SKOV3, and U251 glioma cells. S1 inhibits Bcl-2 and Mcl-1 expression and induces cancer cell apoptosis. Cancer cell survival is highly dependent on glucose. Here, we observ...

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Detalles Bibliográficos
Autores principales: Zhou, Li, Kong, Qinghuan, Zhang, Yunhan, Yang, Wei, Yan, Shan, Li, Meihui, Wang, Yidan, Zhou, Yanjie, Yu, Huimei, Han, Liying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260140/
https://www.ncbi.nlm.nih.gov/pubmed/30538566
http://dx.doi.org/10.2147/CMAR.S184180

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260140/
https://www.ncbi.nlm.nih.gov/pubmed/30538566
http://dx.doi.org/10.2147/CMAR.S184180

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