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Glucose deprivation promotes apoptotic response to S1 by enhancing autophagy in human cervical cancer cells

BACKGROUND: S1 is a novel BH3 mimetic that can induce death in some types of cancer cells, such as melanoma B16, ovarian cancer SKOV3, and U251 glioma cells. S1 inhibits Bcl-2 and Mcl-1 expression and induces cancer cell apoptosis. Cancer cell survival is highly dependent on glucose. Here, we observ...

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Detalles Bibliográficos
Autores principales:	Zhou, Li, Kong, Qinghuan, Zhang, Yunhan, Yang, Wei, Yan, Shan, Li, Meihui, Wang, Yidan, Zhou, Yanjie, Yu, Huimei, Han, Liying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2018
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260140/ https://www.ncbi.nlm.nih.gov/pubmed/30538566 http://dx.doi.org/10.2147/CMAR.S184180

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