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Non-coding Class Switch Recombination-Related Transcription in Human Normal and Pathological Immune Responses
Antibody class switch recombination (CSR) to IgG, IgA, or IgE is a hallmark of adaptive immunity, allowing antibody function diversification beyond IgM. CSR involves a deletion of the IgM/IgD constant region genes placing a new acceptor Constant gene, downstream of the VDJ(H) exon. CSR depends on no...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260145/ https://www.ncbi.nlm.nih.gov/pubmed/30519242 http://dx.doi.org/10.3389/fimmu.2018.02679 |