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Non-coding Class Switch Recombination-Related Transcription in Human Normal and Pathological Immune Responses

Antibody class switch recombination (CSR) to IgG, IgA, or IgE is a hallmark of adaptive immunity, allowing antibody function diversification beyond IgM. CSR involves a deletion of the IgM/IgD constant region genes placing a new acceptor Constant gene, downstream of the VDJ(H) exon. CSR depends on no...

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Detalles Bibliográficos
Autores principales: Kuri-Magaña, Helena, Collado-Torres, Leonardo, Jaffe, Andrew E., Valdovinos-Torres, Humberto, Ovilla-Muñoz, Marbella, Téllez-Sosa, Juan, Bonifaz, Laura C., Martínez-Barnetche, Jesús
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260145/
https://www.ncbi.nlm.nih.gov/pubmed/30519242
http://dx.doi.org/10.3389/fimmu.2018.02679