Prediction of the Closed Conformation and Insights into the Mechanism of the Membrane Enzyme LpxR

Covalent modification of outer membrane lipids of Gram-negative bacteria can impact the ability of the bacterium to develop resistance to antibiotics as well as modulating the immune response of the host. The enzyme LpxR from Salmonella typhimurium is known to deacylate lipopolysaccharide molecules...

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Detalles Bibliográficos
Autores principales: Saunders, Graham M., Bruce Macdonald, Hannah E., Essex, Jonathan W., Khalid, Syma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2018
Materias:
Proteins
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260217/
https://www.ncbi.nlm.nih.gov/pubmed/30287112
http://dx.doi.org/10.1016/j.bpj.2018.09.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260217/
https://www.ncbi.nlm.nih.gov/pubmed/30287112
http://dx.doi.org/10.1016/j.bpj.2018.09.002

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