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The hidden variables problem in Alzheimer's disease clinical trial design

As the leading cause of dementia worldwide, Alzheimer's disease has garnered intense academic and clinical interest. Yet, trials in search of a disease-modifying therapy have failed overwhelmingly. We suggest that, in part, this may be attributable to the influence of disruptive variables inher...

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Detalles Bibliográficos
Autores principales: Liyanage, S. Imindu, Santos, Clarissa, Weaver, Donald F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260222/
https://www.ncbi.nlm.nih.gov/pubmed/30519628
http://dx.doi.org/10.1016/j.trci.2018.09.003