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Crystal structure of the condensation domain from lovastatin polyketide synthase

The highly reducing iterative polyketide synthases responsible for lovastatin biosynthesis contains a section homologous to condensation (CON) domain observed in nonribosomal peptide synthetases (NRPSs). In the present study, we expressed the isolated lovastatin CON domain and solved the crystal str...

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Detalles Bibliográficos
Autores principales: Wang, Lei, Yuan, Meijuan, Zheng, Jianting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260248/
https://www.ncbi.nlm.nih.gov/pubmed/30533541
http://dx.doi.org/10.1016/j.synbio.2018.11.003