The mouse–canine chimeric anti-dog podoplanin antibody P38B exerts antitumor activity in mouse xenograft models

Podoplanin (PDPN) is a type I transmembrane heavily glycosylated sialoglycoprotein that is expressed in normal tissues such as pulmonary type I alveolar cells, renal podocytes, and lymphatic endothelial cells. PDPN overexpression in cancerous tissue is associated with hematogenous metastasis through...

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Detalles Bibliográficos
Autores principales: Kato, Yukinari, Ohishi, Tomokazu, Kawada, Manabu, Maekawa, Naoya, Konnai, Satoru, Itai, Shunsuke, Yamada, Shinji, Kaneko, Mika K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260363/
https://www.ncbi.nlm.nih.gov/pubmed/30519645
http://dx.doi.org/10.1016/j.bbrep.2018.11.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260363/
https://www.ncbi.nlm.nih.gov/pubmed/30519645
http://dx.doi.org/10.1016/j.bbrep.2018.11.005

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