Characterizing Trastuzumab-Induced Alterations in Intratumoral Heterogeneity with Quantitative Imaging and Immunohistochemistry in HER2+ Breast Cancer

The purpose of this study is to investigate imaging and histology-based measurements of intratumoral heterogeneity to evaluate early treatment response to targeted therapy in a murine model of HER2+ breast cancer. BT474 tumor-bearing mice (N = 30) were treated with trastuzumab or saline and imaged l...

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Detalles Bibliográficos
Autores principales: Syed, Anum K., Woodall, Ryan, Whisenant, Jennifer G., Yankeelov, Thomas E., Sorace, Anna G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2018
Materias:
Original article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260456/
https://www.ncbi.nlm.nih.gov/pubmed/30472501
http://dx.doi.org/10.1016/j.neo.2018.10.008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260456/
https://www.ncbi.nlm.nih.gov/pubmed/30472501
http://dx.doi.org/10.1016/j.neo.2018.10.008

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