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The functional differentiation of the post-PKS tailoring oxygenases contributed to the chemical diversities of atypical angucyclines

Angucyclines are one of the largest families of aromatic polyketides with various chemical structures and bioactivities. Decades of studies have made it easy for us to depict the picture of their early biosynthetic pathways. Two families of oxygenases, the FAD-dependent oxygenases and the ring openi...

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Detalles Bibliográficos
Autores principales: Fan, Keqiang, Zhang, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260466/
https://www.ncbi.nlm.nih.gov/pubmed/30533539
http://dx.doi.org/10.1016/j.synbio.2018.11.001