Non-coding RNA in C9orf72-related amyotrophic lateral sclerosis and frontotemporal dementia: A perfect storm of dysfunction

A hexanucleotide repeat expansion in the first intron/promoter region of C9orf72 is the most common genetic cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Both sense and antisense transcripts exist at the C9orf72 locus but the function of the antisense lncRNA is unkn...

Descripción completa

Detalles Bibliográficos
Autor principal: Douglas, Andrew G.L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260478/
https://www.ncbi.nlm.nih.gov/pubmed/30533567
http://dx.doi.org/10.1016/j.ncrna.2018.09.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260478/
https://www.ncbi.nlm.nih.gov/pubmed/30533567
http://dx.doi.org/10.1016/j.ncrna.2018.09.001

Ejemplares similares