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Multi-arm multi-stage trials can improve the efficiency of finding effective treatments for stroke: a case study
BACKGROUND: Many recent Stroke trials fail to show a beneficial effect of the intervention late in the development. Currently a large number of new treatment options are being developed. Multi-arm multi-stage (MAMS) designs offer one potential strategy to avoid lengthy studies of treatments without...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260683/ https://www.ncbi.nlm.nih.gov/pubmed/30482176 http://dx.doi.org/10.1186/s12872-018-0956-4 |