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Multi-arm multi-stage trials can improve the efficiency of finding effective treatments for stroke: a case study

BACKGROUND: Many recent Stroke trials fail to show a beneficial effect of the intervention late in the development. Currently a large number of new treatment options are being developed. Multi-arm multi-stage (MAMS) designs offer one potential strategy to avoid lengthy studies of treatments without...

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Detalles Bibliográficos
Autores principales: Jaki, Thomas, Wason, James M. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260683/
https://www.ncbi.nlm.nih.gov/pubmed/30482176
http://dx.doi.org/10.1186/s12872-018-0956-4