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The metabolic switch can be activated in a recombinant strain of Streptomyces lividans by a low oxygen transfer rate in shake flasks

BACKGROUND: In Streptomyces, understanding the switch from primary to secondary metabolism is important for maximizing the production of secondary metabolites such as antibiotics, as well as for optimizing recombinant glycoprotein production. Differences in Streptomyces lividans bacterial aggregatio...

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Detalles Bibliográficos
Autores principales: Gamboa-Suasnavart, Ramsés A., Valdez-Cruz, Norma A., Gaytan-Ortega, Gerardo, Reynoso-Cereceda, Greta I., Cabrera-Santos, Daniel, López-Griego, Lorena, Klöckner, Wolf, Büchs, Jochen, Trujillo-Roldán, Mauricio A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260694/
https://www.ncbi.nlm.nih.gov/pubmed/30486842
http://dx.doi.org/10.1186/s12934-018-1035-3