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Ursodeoxycholic acid versus placebo in the treatment of women with intrahepatic cholestasis of pregnancy (ICP) to improve perinatal outcomes: protocol for a randomised controlled trial (PITCHES)

BACKGROUND: Intrahepatic cholestasis of pregnancy (ICP) is the most common liver disorder specific to pregnancy and presents with maternal pruritus, raised concentrations of serum bile acids and abnormal liver function tests. ICP is associated with increased rates of spontaneous and iatrogenic prete...

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Detalles Bibliográficos
Autores principales: Chappell, Lucy C., Chambers, Jenny, Dixon, Peter H., Dorling, Jon, Hunter, Rachael, Bell, Jennifer L., Bowler, Ursula, Hardy, Pollyanna, Juszczak, Edmund, Linsell, Louise, Rounding, Catherine, Smith, Anne, Williamson, Catherine, Thornton, Jim G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260710/
https://www.ncbi.nlm.nih.gov/pubmed/30482254
http://dx.doi.org/10.1186/s13063-018-3018-4