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Linking single-cell measurements of mass, growth rate, and gene expression

Mass and growth rate are highly integrative measures of cell physiology not discernable via genomic measurements. Here, we introduce a microfluidic platform enabling direct measurement of single-cell mass and growth rate upstream of highly multiplexed single-cell profiling such as single-cell RNA se...

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Detalles Bibliográficos
Autores principales: Kimmerling, Robert J., Prakadan, Sanjay M., Gupta, Alejandro J., Calistri, Nicholas L., Stevens, Mark M., Olcum, Selim, Cermak, Nathan, Drake, Riley S., Pelton, Kristine, De Smet, Frederik, Ligon, Keith L., Shalek, Alex K., Manalis, Scott R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260722/
https://www.ncbi.nlm.nih.gov/pubmed/30482222
http://dx.doi.org/10.1186/s13059-018-1576-0