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Linking single-cell measurements of mass, growth rate, and gene expression
Mass and growth rate are highly integrative measures of cell physiology not discernable via genomic measurements. Here, we introduce a microfluidic platform enabling direct measurement of single-cell mass and growth rate upstream of highly multiplexed single-cell profiling such as single-cell RNA se...
Autores principales: | Kimmerling, Robert J., Prakadan, Sanjay M., Gupta, Alejandro J., Calistri, Nicholas L., Stevens, Mark M., Olcum, Selim, Cermak, Nathan, Drake, Riley S., Pelton, Kristine, De Smet, Frederik, Ligon, Keith L., Shalek, Alex K., Manalis, Scott R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260722/ https://www.ncbi.nlm.nih.gov/pubmed/30482222 http://dx.doi.org/10.1186/s13059-018-1576-0 |
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