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Inhibition of TPL2 by interferon-α suppresses bladder cancer through activation of PDE4D
BACKGROUND: Drugs that inhibit the MEK/ERK pathway have therapeutic benefit in bladder cancer treatment but responses vary with patients, for reasons that are still not very clear. Interferon-α (IFN-α) is also used as a therapeutic agent for bladder cancer treatment but the response rate is low. It...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260752/ https://www.ncbi.nlm.nih.gov/pubmed/30482227 http://dx.doi.org/10.1186/s13046-018-0971-4 |