CODEX2: full-spectrum copy number variation detection by high-throughput DNA sequencing

High-throughput DNA sequencing enables detection of copy number variations (CNVs) on the genome-wide scale with finer resolution compared to array-based methods but suffers from biases and artifacts that lead to false discoveries and low sensitivity. We describe CODEX2, as a statistical framework fo...

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Detalles Bibliográficos
Autores principales: Jiang, Yuchao, Wang, Rujin, Urrutia, Eugene, Anastopoulos, Ioannis N., Nathanson, Katherine L., Zhang, Nancy R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260772/
https://www.ncbi.nlm.nih.gov/pubmed/30477554
http://dx.doi.org/10.1186/s13059-018-1578-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260772/
https://www.ncbi.nlm.nih.gov/pubmed/30477554
http://dx.doi.org/10.1186/s13059-018-1578-y

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