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miR-181b/Notch2 overcome chemoresistance by regulating cancer stem cell-like properties in NSCLC

BACKGROUND: Lung cancer stem cells have the ability to self-renew and are resistant to conventional chemotherapy. MicroRNAs (miRNAs) regulate and control the expression and function of many target genes; therefore, miRNA disorders are involved in the pathogenesis of human diseases, such as cancer. H...

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Detalles Bibliográficos
Autores principales: Wang, Xiaoyuan, Meng, Qingwei, Qiao, Wenbo, Ma, Ruishuang, Ju, Weiwei, Hu, Jing, Lu, Hailing, Cui, Jianqi, Jin, Zhao, Zhao, Yanbin, Wang, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260863/
https://www.ncbi.nlm.nih.gov/pubmed/30470250
http://dx.doi.org/10.1186/s13287-018-1072-1