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miR-181b/Notch2 overcome chemoresistance by regulating cancer stem cell-like properties in NSCLC
BACKGROUND: Lung cancer stem cells have the ability to self-renew and are resistant to conventional chemotherapy. MicroRNAs (miRNAs) regulate and control the expression and function of many target genes; therefore, miRNA disorders are involved in the pathogenesis of human diseases, such as cancer. H...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260863/ https://www.ncbi.nlm.nih.gov/pubmed/30470250 http://dx.doi.org/10.1186/s13287-018-1072-1 |